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胰島素信號通路、炎癥信號通路與泛素
作者:中糖院 時間:2021-01-19 13:25:12 瀏覽:82

[1]   Hale LJ, Coward RJ. Insulin signalling to the kidney in health and disease[J]. Clin Sci (Lond), 2013, 124(6):351-370  
[2]   Thameem F, Puppala S, Schneider J, et al. The Gly(972)Arg variant of human IRS1gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling[J]. Diabetes, 2012, 61(9):2385-2393  
[3]   Bedse G, Di Domenico F, Serviddio G, et al. Aberrant insulin signaling in Alzheimer's disease: current knowledge[J]. Front Neurosci, 2015, 9:204  
[5]   Kim OK, Jun W, Lee J. Mechanism of ER stress and inflammation for hepatic insulin resistance in obesity[J]. Ann Nutr Metab, 2015, 67(4):218-227  
[7]   Horita S, Nakamura M, Suzuki M, et al. Selective insulin resistance in the kidney[J]. Biomed Res Int, 2016, 2016:5825170  
[8]   Agarwal P, Srivastava R, Srivastava AK, et al. miR-135a targets IRS2 and regulates insulin signaling and glucose uptake in the diabetic gastrocnemius skeletal muscle[J]. Biochim Biophys Acta, 2013, 1832(8):1294-1303  
[12]   Gregor MF, Hotamisligil GS. Inlammatory mechanisms in obesity[J]. Annu Rev Immunol, 2011, 29:415-445  
[14]   Luft VC, Schmidt MI, Pankow JS, et al. Chronic inflammation role in the obesity-diabetes association: a case-cohort study [J]. Diabetol Metab Syndr, 2013, 5(1):31  
[15]   Wang XH, Mitch WE. Muscle wasting from kidney failure-a model for catabolic conditions [J]. Int J Biochem Cell Biol, 2013, 45(10): 2230-2238  
[19]   Jiao P, Ma J, Feng B, et al. FFA-induced adipocyte inlammation and insulin resistance: involvement of ER stress and IKKβ pathways[J]. Obesity (Silver Spring), 2011, 19(3):483-491  
[21]   Ren F, Zhou L, Zhang X, et al. Endoplasmic reticulum stress-activated glycogen synthase kinase 3β aggravates liver inflammation and hepatotoxicity in mice with acute liver failure[J]. Inflammation, 2015, 38(3):1151-1165  
[22]   Dou L, Zhao T, Wang L, et al. miR-200s contribute to interleukin-6 (IL-6)-induced insulin resistance in hepatocytes[J]. J Biol Chem, 2013, 288(31):22596-22606  
[26]   Tuncman G, Hirosumi J, Solinas G, et al. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance[J].Proc Natl Acad Sci U S A,2006,103(28): 10741-10746  
[28]   Pal M, Wunderlich CM, Spohn G, et al. Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice[J]. PLoS One, 2013, 8(1):e54247  
[29]   Song YH, Li Y, Du J, et al. Muscle-specific expression of insulin-like growth factor-1 blocks angiotensin II-induced skeletal muscle wasting[J]. J Clin Invest, 2005, 115(2):451-458  
[33]   Kim SJ, DeStefano MA, Oh WJ, et al. mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8[J]. Mol Cell, 2012, 48(6):875-887  
[35]   Lin XW, Xu WC, Luo JG, et al. WW domain containing E3 ubiquitin protein ligase 1(WWP1) negatively regulates TLR4-mediated TNF-? and IL-6 production by proteasomal degradation of TNF receptor associated factor 6 (TRAF6) [J]. PLoS One, 2013, 8(6):e67633  
[6]   de Luca C, Olefsky JM. Inflammation and insulin resistance[J].FEBS Lett,2008, 582(1):97-105  
[9]   Könner AC, Brüning JC. Selective insulin and leptin resistance in metabolic disorders [J]. Cell Metab, 2012, 16(2):144-152  
[11]   Baumann CA, Ribon V, Kanzaki M, et al. CAP de?nes a second signalling pathway required for insulin-stimulated glucose transport[J]. Nature, 2000, 407(6801):202-207  
[13]   Ouchi N, Parker JL, Lugus JJ, et al. Adipokines in inlammation and metabolic disease[J]. Nat Rev Immunol, 2011, 11(2):85-97  
[16]   Rahman MM, McFadden G. Modulation of NF-κB signalling by microbial pathogens[J]. Nat Rev Microbiol, 2011, 9(4):291-306  
[18]   Yuan M, Konstantopoulos N, Lee J, et al. Reversal of obesity- and diet-induced insulin resistance with salicylates ortargeted disruption of Ikkbeta[J].Science,2001,293(5535): 1673- 1677  
[20]   Chen L, Chen R, Wang H, et al. Mechanisms linking inflammation to insulin resistance[J]. Int J Endocrinol, 2015, 2015:508409  
[23]   Yin J, Hao Z, Ma Y, et al. Concomitant activation of the PI3K/Akt and ERK1/2 signalling is involved in cyclic compressive force-induced IL-6 secretion in MLO-Y4 cells[J]. Cell Biol Int, 2014, 38(5):591-598  
[25]   Sabio G, Das M, Mora A, et al. A stress signaling pathway in adipose tissue regulates hepatic insulin resistance[J]. Science, 2008, 322(5907):1539-1543  
[27]   Han MS, Jung DY, Morel C, et al. JNK expression by macrophages promotes obesity- induced insulin resistance and in?ammation[J]. Science, 2013, 339(6116):218-222  
[30]   Lecker SH, Jagoe RT, Gilbert A, et al. Multiple types of skeletal muscle atrophy involve a commonprogram of changes in gene expression[J]. FASEB J, 2004, 18(1):39-51  
[32]   Zhou Q, Du J, Hu Z, et al. Evidence for adipose-muscle cross talk: opposing regulation of muscle proteolysis by adiponectin and fatty acids[J]. Endocrinology, 2007, 148(12): 5696-5705  
[34]   Abe T, Hirasaka K, Kohno S, et al. Ubiquitin ligase Cbl-b and obesity-induced insulin resistance[J]. Endocr J, 2014, 61(6):529-538  
[36]   Lee YS, Park JS, Kim JH, et al. Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of My D88 in TLR4 signalling[J]. Nat Commun, 2011, 2:460  
[10]   Usui I, Imamura T, Huang J, et al. Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes[J]. J Biol Chem, 2003, 278 (16): 13765- 13774  
[17]   Su D, Coudriet GM, Hyun Kim D, et al. FoxO1 links insulin resistance to proinlammatory cytokine IL-1β production in macrophages[J]. Diabetes, 2009, 58(11):2624-2633  
[24]   Hotamisligil GS. Endoplasmic reticulum stress and the in?ammatory basis of metabolic disease[J]. Cell, 2010, 140(6):900-917  
[31]   Hu Z, Lee IH, Wang X, et al. PTEN expression contributes to the regulation of muscle protein degradation in diabetes[J]. Diabetes, 2007, 56(10):2449-2456  
[4]   Syed Ikmal SI, Zaman Huri H, Vethakkan SR, et al. Potential biomarkers of insulin resistance and atherosclerosis in type 2 diabetes mellitus patients with coronary artery disease[J]. Int J Endocrinol, 2013, 2013:698567  


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